Journal of Pharmacognosy and Phytotherapy

The aim of this study was to investigate the anthelmintic effect of pumpkin seeds (Cucurbita maxima) against Aspiculuris tetraptera in naturally infected mice.For this purpose, the natural infection was determined by the cellophane tape (on the anal region), and the centrifugal flotation methods of stool samples in approximately 150 male Swiss albino mice (27 to 35 g).The infected mice (29 animals) were divided into four groups.The animals in the first (G 1 ) and second groups (G 2 ) received water and ethanol extracts of pumpkin seeds orally at the dose suggested for human for 7 days, respectively.The mice in the positive control group (G 3 ) were treated with ivermectin intramuscularly at a dose of 0.2 mg/kg…