articleJournal of Clinical InvestigationNov 15, 2002Closed access

Orchestrating the unfolded protein response in health and disease

RJRandal J. Kaufman

Howard Hughes Medical Institute · University of Michigan · +1 more institution

Indexed incrossrefdoaj

Abstract

Nonstandard abbreviations used: endoplasmic reticulum (ER); unfolded protein response (UPR); basic leucine zipper (bZIP); UPR element (UPRE); endoplasmic reticulum stress response element (ERSE); site-1 protease (S1P); site-2 protease (S2P); sterol-response element-binding protein (SREBP); eukaryotic translation initiation factor 2 (eIF2); endoplasmic reticulum-associated degradation (ERAD); α1-proteinase

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1,002
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Topics & keywords

Topics
Keywords
  • Unfolded protein response
  • Disease
  • Medicine
  • Computational biology
  • Biology
  • Endoplasmic reticulum
  • Cell biology
  • Internal medicine
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