African Journal of Biochemistry Research

Lead (Pb) is one of the toxic metals and is commonly used in industries.It affects multiple systems and has role in the production of reactive oxygen species (ROS).The objective of the present study was to determine Pb levels and to detect DNA damage in traffic wardens of Lahore, Pakistan.A total of 90 subjects were selected including 60 traffic wardens working in field and 30 working in administrative zones.The wardens who were working in field were considered as cases (exposed by the lead polluted environment) while the wardens in the administrative offices (less exposed to polluted environment) were labeled controls.Venous blood samples were collected for Pb and comet assay.In cases, the levels of Pb were…