BeStSel: webserver for secondary structure and fold prediction for protein CD spectroscopy
Eötvös Loránd University · Synchrotron soleil · +8 more institutions
Abstract
Circular dichroism (CD) spectroscopy is widely used to characterize the secondary structure composition of proteins. To derive accurate and detailed structural information from the CD spectra, we have developed the Beta Structure Selection (BeStSel) method (PNAS, 112, E3095), which can handle the spectral diversity of β-structured proteins. The BeStSel webserver provides this method with useful accessories to the community with the main goal to analyze single or multiple protein CD spectra. Uniquely, BeStSel provides information on eight secondary structure components including parallel β-structure and antiparallel β-sheets with three different groups of twist. It overperforms any available method in accuracy…
Citation impact
- FWCI
- 33.70
- Percentile
- 100%
- References
- 50
Authors
12Topics & keywords
- Protein secondary structure
- Web server
- In silico
- Biology
- Antiparallel (mathematics)
- Circular dichroism
- Computational biology
- Protein Data Bank (RCSB PDB)