Immunoregulation in Diabetic Wound Repair with a Photoenhanced Glycyrrhizic Acid Hydrogel Scaffold
Wenzhou Medical University · Zhejiang Lab · +4 more institutions
Abstract
Abstract M1 macrophage accumulation and excessive inflammation are commonly encountered issues in diabetic wounds and can fail in the healing process. Hence, hydrogel dressings with immunoregulatory capacity have great promise in the clinical practice of diabetic wound healing. However, current immunoregulatory hydrogels are always needed for complex interventions and high‐cost treatments, such as cytokines and cell therapies. In this study, a novel glycyrrhizic acid (GA)‐based hybrid hydrogel dressing with intrinsic immunoregulatory properties is developed to promote rapid diabetic wound healing. This hybrid hydrogel consists of interpenetrating polymer networks composed of inorganic Zn 2+ ‐induced…
Citation impact
- FWCI
- 61.70
- Percentile
- 100%
- References
- 74
Authors
10- YQYuna Qian
Wenzhou Medical University, Zhejiang Lab, University of Chinese Academy of Sciences
- YZYujing Zheng
Wenzhou Medical University
- JJJuan Jin
Zhejiang Provincial People's Hospital, Hangzhou Medical College
- XWXuan Wu
Zhejiang Lab, University of Chinese Academy of Sciences
- KXKejia Xu
Wenzhou Medical University
Topics & keywords
- Self-healing hydrogels
- Scaffold
- Fibroin
- Wound healing
- Materials science
- Wound dressing
- Inflammation
- Nanotechnology
- Good health and well-being