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reviewMoleculesMay 17, 2022GOLD OA

RETRACTED: Neuroinflammatory Markers: Key Indicators in the Pathology of Neurodegenerative Diseases

ARAbdur RaufHBHimani BadoniTATareq Abu‐IzneidAOAhmed OlatundeMMMd. Mominur Rahman

University of Swabi · Uttaranchal University · +8 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

Neuroinflammation, a protective response of the central nervous system (CNS), is associated with the pathogenesis of neurodegenerative diseases. The CNS is composed of neurons and glial cells consisting of microglia, oligodendrocytes, and astrocytes. Entry of any foreign pathogen activates the glial cells (astrocytes and microglia) and overactivation of these cells triggers the release of various neuroinflammatory markers (NMs), such as the tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), interleukin-1β (IL-10), nitric oxide (NO), and cyclooxygenase-2 (COX-2), among others. Various studies have shown the role of neuroinflammatory markers in the occurrence, diagnosis, and treatment of neurodegenerative…

Citation impact

287
total citations
FWCI
22.09
Percentile
100%
References
258
Citations per year

Authors

9

Topics & keywords

Topics
Keywords
  • Neuroinflammation
  • Microglia
  • Multiple sclerosis
  • Neuroscience
  • Disease
  • Neurodegeneration
  • Medicine
  • Central nervous system
UN Sustainable Development Goals
  • Good health and well-being
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