articleNature MedicineMay 10, 2022HYBRID OA

Modeling transmission of SARS-CoV-2 Omicron in China

Fudan University · National Institutes of Health · +4 more institutions

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Abstract

Having adopted a dynamic zero-COVID strategy to respond to SARS-CoV-2 variants with higher transmissibility since August 2021, China is now considering whether, and for how long, this policy can remain in place. The debate has thus shifted towards the identification of mitigation strategies for minimizing disruption to the healthcare system in the case of a nationwide epidemic. To this aim, we developed an age-structured stochastic compartmental susceptible-latent-infectious-removed-susceptible model of SARS-CoV-2 transmission calibrated on the initial growth phase for the 2022 Omicron outbreak in Shanghai, to project COVID-19 burden (that is, number of cases, patients requiring hospitalization and intensive…

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Authors

18

Topics & keywords

Keywords
  • Transmissibility (structural dynamics)
  • Transmission (telecommunications)
  • Psychological intervention
  • Medicine
  • Coronavirus disease 2019 (COVID-19)
  • Vaccination
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
  • Outbreak
UN Sustainable Development Goals
  • Good health and well-being
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