reviewSignal Transduction and Targeted TherapyMay 21, 2022GOLD OA

mRNA-based therapeutics: powerful and versatile tools to combat diseases

Sichuan University · State Key Laboratory of Biotherapy · +1 more institution

PubMed
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Abstract

The therapeutic use of messenger RNA (mRNA) has fueled great hope to combat a wide range of incurable diseases. Recent rapid advances in biotechnology and molecular medicine have enabled the production of almost any functional protein/peptide in the human body by introducing mRNA as a vaccine or therapeutic agent. This represents a rising precision medicine field with great promise for preventing and treating many intractable or genetic diseases. In addition, in vitro transcribed mRNA has achieved programmed production, which is more effective, faster in design and production, as well as more flexible and cost-effective than conventional approaches that may offer. Based on these extraordinary advantages, mRNA…

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