Association Between Psoriasis and Nonalcoholic Fatty Liver Disease Among Outpatient US Adults

Recent studies have shown an association between psoriasis and nonalcoholic fatty liver disease (NAFLD) in US inpatients, but the association is still unclear in the outpatient US population.

To assess whether psoriasis is associated with NAFLD in outpatient US adults. Design, Setting, and Participants: This population-based cross-sectional study used data on US adults aged 20 to 59 years from the National Health and Nutrition Examination Survey (NHANES) 2003-2006 and 2009-2014 cycles. Data were analyzed from June to September 2021. Exposures: Self-reported psoriasis. Main Outcomes and Measures: The main outcome was NAFLD, defined as a US fatty liver index score greater than 30. Sampling weights were calculated according to NHANES guidelines.