Dissolving microneedles: Applications and growing therapeutic potential
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Abstract
Microneedles are a rapidly developing method for the transdermal delivery of therapeutic compounds. All types of microneedles, whether solid, hollow, coated, or dissolving function by penetrating the stratum corneum layer of the skin producing a microchannel through which therapeutic agents may be delivered. To date, coated and hollow microneedles have been the most successful, despite suffering from issues such as poor drug loading capabilities and blocked pores. Dissolving microneedles, on the other hand, have superior drug loading as well as other positive attributes that make it an ideal delivery system, including simple methods of fabrication and disposal, and abundantly available materials. Indeed,…
Citation impact
449
total citations
- FWCI
- 31.33
- Percentile
- 100%
- References
- 126
Citations per year
Authors
3Topics & keywords
Topics
Keywords
- Transdermal
- Nanotechnology
- Drug delivery
- Materials science
- Stratum corneum
- Biomedical engineering
- Medicine
- Pharmacology
UN Sustainable Development Goals
- Good health and well-being
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