The LOTUS initiative for open knowledge management in natural products research
University of Geneva · HES-SO University of Applied Sciences and Arts Western Switzerland · +10 more institutions
Abstract
Contemporary bioinformatic and chemoinformatic capabilities hold promise to reshape knowledge management, analysis and interpretation of data in natural products research. Currently, reliance on a disparate set of non-standardized, insular, and specialized databases presents a series of challenges for data access, both within the discipline and for integration and interoperability between related fields. The fundamental elements of exchange are referenced structure-organism pairs that establish relationships between distinct molecular structures and the living organisms from which they were identified. Consolidating and sharing such information via an open platform has strong transformative potential for…
Citation impact
- FWCI
- 64.56
- Percentile
- 100%
- References
- 144
Authors
15- ARAdriano Rutz
University of Geneva, HES-SO University of Applied Sciences and Arts Western Switzerland
- MSMaria Sorokina
Friedrich Schiller University Jena
- JGJakub Galgonek
Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry
- DMDaniel Mietchen
Leibniz Institute of Freshwater Ecology and Inland Fisheries, Ronin Institute, University of Virginia
- EWEgon Willighagen
Maastricht University
Topics & keywords
- Interoperability
- Data curation
- Computer science
- Data science
- World Wide Web
- Data sharing
- Knowledge base
- Knowledge management
Funding
- NSNational Science Foundation
- OOOffice of Dietary SupplementsAward: P50 AT000155
- APAlfred P. Sloan FoundationAward: G-2019-11458
- DFDeutsche ForschungsgemeinschaftAwards: SFB 1127, 239748522
- SNSchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen ForschungAwards: U41 AT008706, CRSII5_189921
- MŠMinisterstvo Školství, Mládeže a TělovýchovyAward: LM2018131
- IDInstituto de Desenvolvimento Sustentável Mamirauá
- NINational Institutes of HealthAwards: P50 AT000155, U41 AT008706, AT000155
- NCNational Center for Complementary and Integrative HealthAwards: P50 AT000155, AT000155, U41 AT008706