articleAlzheimer s & DementiaJun 2, 2022GREEN OA

Global estimates on the number of persons across the Alzheimer's disease continuum

Karolinska Institutet · Quantify Research (Sweden) · +16 more institutions

PubMed
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Abstract

Introduction

Global estimates on numbers of persons in early stages of Alzheimer's disease (AD), including prodromal and preclinical, are lacking, yet are needed to inform policy decisions on preventive measures and planning for future therapies targeting AD pathology.

Methods

We synthesized the literature on prevalence across the AD continuum and derived a model estimating the number of persons, stratified by 5-year age groups, sex, and disease stage (AD dementia, prodromal AD, and preclinical AD).

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Funding