reviewBiomoleculesJun 4, 2022GOLD OA

Nano-Based Approved Pharmaceuticals for Cancer Treatment: Present and Future Challenges

FRFrancisco RodríguezPCPablo CaruanaNDNoa De la FuentePEPía EspañolMRMaría Rodríguez Gámez

Hospital de Sant Pau · Universitat Autònoma de Barcelona · +1 more institution

PubMed
Indexed incrossrefdoajpubmed

Abstract

Cancer is one of the main causes of death worldwide. To date, and despite the advances in conventional treatment options, therapy in cancer is still far from optimal due to the non-specific systemic biodistribution of antitumor agents. The inadequate drug concentrations at the tumor site led to an increased incidence of multiple drug resistance and the appearance of many severe undesirable side effects. Nanotechnology, through the development of nanoscale-based pharmaceuticals, has emerged to provide new and innovative drugs to overcome these limitations. In this review, we provide an overview of the approved nanomedicine for cancer treatment and the rationale behind their designs and applications. We also…

Citation impact

250
total citations
FWCI
18.00
Percentile
100%
References
219
Citations per year

Authors

12

Topics & keywords

Topics
Keywords
  • Nanomedicine
  • Medicine
  • Cancer
  • Cancer treatment
  • Nanotechnology
  • Biodistribution
  • Cancer therapy
  • Intensive care medicine
UN Sustainable Development Goals
  • Good health and well-being
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