ColabFold: making protein folding accessible to all
Max Planck Institute for the Study of Religious and Ethnic Diversity · Max Planck Institute for Multidisciplinary Sciences · +7 more institutions
Abstract
ColabFold offers accelerated prediction of protein structures and complexes by combining the fast homology search of MMseqs2 with AlphaFold2 or RoseTTAFold. ColabFold's 40-60-fold faster search and optimized model utilization enables prediction of close to 1,000 structures per day on a server with one graphics processing unit. Coupled with Google Colaboratory, ColabFold becomes a free and accessible platform for protein folding. ColabFold is open-source software available at https://github.com/sokrypton/ColabFold and its novel environmental databases are available at https://colabfold.mmseqs.com .
Citation impact
- FWCI
- 772.77
- Percentile
- 100%
- References
- 35
Authors
6- MMMilot MirditaCorresponding
Max Planck Institute for the Study of Religious and Ethnic Diversity, Max Planck Institute for Multidisciplinary Sciences
- KSKonstantin Schütze
Seoul National University
- YMYoshitaka Moriwaki
The University of Tokyo
- LHLim Heo
Michigan State University
- SOSergey OvchinnikovCorresponding
Harvard University Press, Center for Systems Biology
Topics & keywords
- Computer science
- Protein folding
- Folding (DSP implementation)
- Software
- Graphics processing unit
- Molecular graphics
- Open source software
- Graphics
Funding
- NSNational Science FoundationAward: MCB2032259
- JAJapan Agency for Medical Research and DevelopmentAward: JP21am0101107
- NRNational Research FoundationAward: 2019R1A6A1A10073437
- BFBundesministerium für Bildung und Forschung
- SNSeoul National University
- GGGeorg-August-Universität Göttingen
- NRNational Research Foundation of KoreaAwards: 2019R1A6A1A10073437, 2020M3A9G7103933, 2021R1C1C102065, 2021M3A9I4021220, 2021R1C1C102065, 2019R1A6A1A10073437, 2021M3A9I4021220, 2020M3A9G7103933
- MMax-Planck-Gesellschaft
- NINational Institutes of HealthAward: DP5OD026389