reviewPhysiological ReviewsJun 9, 2022GREEN OA

Human temperature regulation under heat stress in health, disease, and injury

Defence Research and Development Canada · Montreal Heart Institute · +6 more institutions

PubMed
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Abstract

The human body constantly exchanges heat with the environment. Temperature regulation is a homeostatic feedback control system that ensures deep body temperature is maintained within narrow limits despite wide variations in environmental conditions and activity-related elevations in metabolic heat production. Extensive research has been performed to study the physiological regulation of deep body temperature. This review focuses on healthy and disordered human temperature regulation during heat stress. Central to this discussion is the notion that various morphological features, intrinsic factors, diseases, and injuries independently and interactively influence deep body temperature during exercise and/or…

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