reviewRSC AdvancesJan 1, 2022GOLD OA

Pyridine: the scaffolds with significant clinical diversity

Adamas University · Vellore Institute of Technology University

PubMed
Indexed incrossrefdoajpubmed

Abstract

The nitrogen-bearing heterocycle pyridine in its several analogous forms occupies an important position as a precious source of clinically useful agents in the field of medicinal chemistry research. This privileged scaffold has been consistently incorporated in a diverse range of drug candidates approved by the FDA (Food and Drug Administration). This moiety has attracted increasing attention from several disease states owing to its ease of parallelization and testing potential pertaining to the chemical space. In the next few years, a larger share of novel pyridine-based drug candidates is expected. This review unifies the current advances in novel pyridine-based molecular frameworks and their unique clinical…

Citation impact

300
total citations
FWCI
28.73
Percentile
100%
References
82
Citations per year

Authors

7

Topics & keywords

Keywords
  • Diversity (politics)
  • Pyridine
  • Chemistry
  • Organic chemistry
  • Sociology
  • Anthropology
UN Sustainable Development Goals
  • Zero hunger
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