Proteolysis-targeting chimera (PROTAC) delivery system: advancing protein degraders towards clinical translation
University of Wisconsin–Madison · University of Wisconsin Carbone Cancer Center
Indexed incrossrefpubmed
Abstract
Degradation efficacy of PROTACs through delivery strategies, outline design principles for PROTAC-based delivery systems, discuss the current challenges with PROTACs, and outlook future opportunities in this field.
Citation impact
267
total citations
- FWCI
- 19.49
- Percentile
- 100%
- References
- 59
Citations per year
Authors
6- YCYu Chen
University of Wisconsin–Madison, University of Wisconsin Carbone Cancer Center
- ITIra Tandon
University of Wisconsin–Madison
- WJWilliam J. Heelan
University of Wisconsin–Madison
- YWYixin Wang
University of Wisconsin–Madison, University of Wisconsin Carbone Cancer Center
- WTWeiping TangCorresponding
University of Wisconsin–Madison
Topics & keywords
Topics
Keywords
- Protein degradation
- Biology
- Cell biology
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