articleFrontiers in PharmacologyJun 28, 2022GOLD OA

Comprehensive Analysis of Cuproptosis-Related Genes in Immune Infiltration and Prognosis in Melanoma

HLHaozhen LvXLXiao LiuXZXuanhao ZengYLYating LiuCZCan-Jing Zhang

Fudan University · Huashan Hospital

PubMed
Indexed incrossrefdoajpubmed

Abstract

Skin cutaneous melanoma (SKCM, hereafter referred to as melanoma) is the most lethal skin cancer with increasing incidence. Regulated cell death plays an important role in tumorigenesis and serves as an important target for almost all treatment strategies. Cuproptosis is the most recently identified copper-dependent regulated cell death form that relies on mitochondria respiration. However, its role in tumorigenesis remains unknown. The correlation of cuproptosis-related genes with tumor prognosis is far to be understood, either. In the present study, we explored the correlation between cuproptosis-related genes with the prognosis of melanoma by accessing and analyzing a public database and found 11 out 12…

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Authors

7

Topics & keywords

Topics
Keywords
  • Melanoma
  • Carcinogenesis
  • Cancer research
  • Skin cancer
  • Cancer
  • Gene
  • Immunotherapy
  • Gene expression
UN Sustainable Development Goals
  • Good health and well-being
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