Monkeypox virus: a re-emergent threat to humans

Human monkeypox (MPX) is a rare zoonotic infection characterized by smallpox-like signs and symptoms. It is caused by monkeypox virus (MPXV), a double stranded DNA virus belonging to the genus Orthopoxvirus. MPX was first identified in 1970 and mostly prevailed in the rural rainforests of Central and West Africa in the past. Outside Africa, MPX was reported in the United Kingdom, the USA, Israel, and Singapore. In 2022, the resurgence of MPX in Europe and elsewhere posed a potential threat to humans. MPXV was transmitted by the animals-human or human-human pathway, and the symptoms of MPXV infection are similar to that of smallpox, but in a milder form and with lower mortality (1%-10%). Although the smallpox…

• HP
  Hebei Provincial Department of Human Resources and Social Security

  Award: C20200344
• NN
  National Natural Science Foundation of China

  Award: 81902026
• DO
  Department of Education of Hebei Province

  Award: BJ2020018
• NS
  Natural Science Foundation of Hebei Province

  Award: H2020206352