reviewMarine DrugsJul 17, 2022GOLD OA

Chitin and Chitosan: Prospective Biomedical Applications in Drug Delivery, Cancer Treatment, and Wound Healing

University of Toronto

PubMed
Indexed incrossrefdoajpubmed

Abstract

Chitin and its derivative chitosan are highly abundant polymers in nature, appearing in both the shells and exoskeletons of various marine and non-marine species. Since they possess favorable properties, such as biocompatibility, biodegradability, non-toxicity, and non-immunogenicity, they have gained recent attention due to their enormous potential biomedical applications. The polycationic surface of chitosan enables it to form hydrogenic and ionic bonds with drug molecules, which is one of its most useful properties. Because chitosan is biocompatible, it can therefore be used in drug delivery systems. The development of chitosan-based nanoparticles has also contributed to the significance of chitin as a drug…

Citation impact

268
total citations
FWCI
19.03
Percentile
100%
References
76
Citations per year

Authors

2

Topics & keywords

Keywords
  • Chitin
  • Chitosan
  • Biocompatibility
  • Drug delivery
  • Nanotechnology
  • Tissue engineering
  • Chemistry
  • Materials science
UN Sustainable Development Goals
  • Life below water
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