The EWAS Catalog: a database of epigenome-wide association studies

Epigenome-wide association studies (EWAS) seek to quantify associations between traits/exposures and DNA methylation measured at thousands or millions of CpG sites across the genome. In recent years, the increase in availability of DNA methylation measures in population-based cohorts and case-control studies has resulted in a dramatic expansion of the number of EWAS being performed and published. To make this rich source of results more accessible, we have manually curated a database of CpG-trait associations (with p<1x10-4) from published EWAS, each assaying over 100,000 CpGs in at least 100 individuals. From January 7, 2022, The EWAS Catalog contained 1,737,746 associations from 2,686 EWAS. This includes…

• WT
  Wellcome Trust

  Award: 203746
• NI
  National Institute for Health and Care Research

  Awards: NF-SI-0611-10196, MC_UU_12013/1, 217065/Z/19/Z, BB/I025263/1, BB/I025751/1, MC_UU_00011/4, SI-0611-10196, MC_UU_00011/1
• BH
  British Heart Foundation

  Awards: MC_UU_00011/1, SP/07/008/24066
• UO
  University of Bristol

  Awards: MC_UU_00011/4, MC_UU_12013/1, 217065/Z/19/Z, MC_UU_00011/1, MC_UU_12013/4, BB/I025751/1, BB/I025263/1, MC_UU_12013/2
• MR
  Medical Research Council

  Awards: 217065/Z/19/Z, MC_UU_00011/4, MC_UU_12013, 217065, MC_UU_12013/4, MR/S036520/1, MC_UU_12013/1, MC_UU_12013/2, MC_UU_00011/5, MC_UU_00011/4, MR/S009310/1, MC_UU_12013/1, MC_PC_15018, MC_UU_12013/2, MC_UU_00011/1, MC_UU_00011/1, MC_PC_19009, MC_UU_00011
• BA
  Biotechnology and Biological Sciences Research Council

  Awards: BB/I025751/1 and BB/I025263/1, BB/I025263/1, ES/N000498/1, MC_UU_00011/1, BB/I025751/1, MC_UU_00011/4, BB/I025751/1, BB/I025263/1
• EA
  Economic and Social Research Council

  Awards: ES/N000498/1, ES/N000498/1