articleNature MedicineJul 25, 2022HYBRID OA

Symptoms and risk factors for long COVID in non-hospitalized adults

ASAnuradhaa SubramanianKNKrishnarajah NirantharakumarSHSarah HughesPMPuja MylesTWTim Williams

University of Birmingham · Health Data Research UK · +12 more institutions

PubMed
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Abstract

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is associated with a range of persistent symptoms impacting everyday functioning, known as post-COVID-19 condition or long COVID. We undertook a retrospective matched cohort study using a UK-based primary care database, Clinical Practice Research Datalink Aurum, to determine symptoms that are associated with confirmed SARS-CoV-2 infection beyond 12 weeks in non-hospitalized adults and the risk factors associated with developing persistent symptoms. We selected 486,149 adults with confirmed SARS-CoV-2 infection and 1,944,580 propensity score-matched adults with no recorded evidence of SARS-CoV-2 infection. Outcomes included 115 individual…

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Topics & keywords

Topics
Keywords
  • Medicine
  • Anosmia
  • Hazard ratio
  • Cohort
  • Retrospective cohort study
  • Cohort study
  • Internal medicine
  • Proportional hazards model
UN Sustainable Development Goals
  • Good health and well-being
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