reviewStem Cell Research & TherapyJul 28, 2022GOLD OA

Clinical application of mesenchymal stem cell in regenerative medicine: a narrative review

University of Indonesia · Universitas Dr. Soetomo · +11 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

The multipotency property of mesenchymal stem cells (MSCs) has attained worldwide consideration because of their immense potential for immunomodulation and their therapeutic function in tissue regeneration. MSCs can migrate to tissue injury areas to contribute to immune modulation, secrete anti-inflammatory cytokines and hide themselves from the immune system. Certainly, various investigations have revealed anti-inflammatory, anti-aging, reconstruction, and wound healing potentials of MSCs in many in vitro and in vivo models. Moreover, current progresses in the field of MSCs biology have facilitated the progress of particular guidelines and quality control approaches, which eventually lead to clinical…

Citation impact

393
total citations
FWCI
54.84
Percentile
100%
References
164
Citations per year

Authors

13

Topics & keywords

Keywords
  • Mesenchymal stem cell
  • Regenerative medicine
  • Wound healing
  • Immune system
  • Regeneration (biology)
  • Stem cell
  • Clinical uses of mesenchymal stem cells
  • Biology
UN Sustainable Development Goals
  • Good health and well-being
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