Energy-Transfer-Enabled Dearomative Cycloaddition Reactions of Indoles/Pyrroles via Excited-State Aromatics
ShanghaiTech University · Shanghai Institute of Organic Chemistry · +2 more institutions
Abstract
ConspectusExploring the enormous chemical space through an expedient building-up of molecular diversity is an important goal of organic chemistry. The development of synthetic methods toward molecules with unprecedented structural motifs lays the foundation for wide applications ranging from pharmaceutical chemistry to materials science. In this regard, the dearomatization of arenes has been recognized as a unique strategy since it provides novel retrosynthetic disconnections for various spiro or fused polycyclic molecules with increased saturation and stereoisomerism. However, inherent thermodynamic challenges are associated with dearomatization processes. The disruption of the aromaticity of arene substrates…
Citation impact
- FWCI
- 22.81
- Percentile
- 100%
- References
- 70
Authors
4- MZMin Zhu
ShanghaiTech University, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences
- XZXiǎo ZhangCorresponding
Fujian Normal University, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences
- CZChao ZhengCorresponding
Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences
- SYShu‐Li YouCorresponding
ShanghaiTech University, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences
Topics & keywords
- Chemistry
- Cycloaddition
- Excited state
- Aromaticity
- Molecule
- Combinatorial chemistry
- Computational chemistry
- Nanotechnology
- Affordable and clean energy
Funding
- TTencent
- NNNational Natural Science Foundation of ChinaAwards: 22171282, 21821002, 22071024, 91856201, 22031012
- CAChinese Academy of SciencesAward: Y2021075
- MOMinistry of Science and Technology of the People's Republic of ChinaAward: 2021YFA1500100
- SAScience and Technology Commission of Shanghai MunicipalityAwards: 22JC1401103, 21520780100, 19590750400