articleNew England Journal of MedicineFeb 27, 2008Closed access

Systemic Lupus Erythematosus

University College London

PubMed
Indexed incrossrefpubmed

Abstract

Systemic lupus erythematosus has many guises, but the unifying feature is the presence of antibodies against double-stranded DNA in almost all patients. This review provides data that show that such autoantibodies cause the renal lesions of systemic lupus erythematosus, and it emphasizes the importance of histones, histone fragments, and other nuclear autoantigens.

Citation impact

1,632
total citations
FWCI
63.49
Percentile
100%
References
85
Citations per year

Authors

2

Topics & keywords

Keywords
  • Medicine
  • Autoantibody
  • Immunology
  • Histone
  • Lupus erythematosus
  • Systemic lupus erythematosus
  • Antibody
  • Blisibimod
UN Sustainable Development Goals
  • Good health and well-being
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