articleNew England Journal of MedicineSep 21, 2005Closed access

Primary Biliary Cirrhosis

MMMarshall M. KaplanMEM. Eric Gershwin

Tufts Medical Center · University of California, Davis

PubMed
Indexed incrossrefpubmed

Abstract

Primary biliary cirrhosis, a slowly progressive autoimmune liver disease characterized by portal inflammation and an immune-mediated destruction of the intrahepatic bile ducts, leads to decreased bile secretion and the retention of toxic substances within the liver. This review considers new data concerning both the autoimmune responses involved and the treatment of primary biliary cirrhosis.

Citation impact

1,148
total citations
FWCI
31.00
Percentile
100%
References
93
Citations per year

Authors

2

Topics & keywords

Topics
Keywords
  • Primary biliary cirrhosis
  • Medicine
  • Cirrhosis
  • Gastroenterology
  • Biliary cirrhosis
  • Intrahepatic bile ducts
  • Internal medicine
  • Immune system
UN Sustainable Development Goals
  • Good health and well-being
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