articleInternational Journal of Molecular SciencesAug 23, 2022GOLD OA

Investigation of the Associations of Novel Inflammatory Biomarkers—Systemic Inflammatory Index (SII) and Systemic Inflammatory Response Index (SIRI)—With the Severity of Coronary Artery Disease and Acute Coronary Syndrome Occurrence

EAEwelina A. DziedzicJSJakub S. GąsiorATAgnieszka TuzimekJPJustyna PalecznyAJAdam Junka

Uczelnia Łazarskiego · Postgraduate School of Molecular Medicine · +2 more institutions

PubMed
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Abstract

Atherosclerosis, the underlying cause of coronary artery disease (CAD), has a significant inflammatory component. White blood cell count is an affordable and accessible way to assess the systemic immune response, as it comprises many subgroups with distinct and complex functions. Considering their multidirectional effect on atherosclerosis, new biomarkers integrating various leukocyte subgroups, the Systemic Inflammatory Index (SII) and the Systemic Inflammatory Response Index (SIRI), were recently devised to describe the balance between inflammation and immune reaction. This research aimed to evaluate the relationship of the intensity of inflammation measured by these biomarkers with the severity of CAD…

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301
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41.53
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100%
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Authors

7

Topics & keywords

Topics
Keywords
  • Medicine
  • Coronary artery disease
  • Acute coronary syndrome
  • Systemic inflammation
  • Internal medicine
  • Inflammation
  • Cardiology
  • Systemic inflammatory response syndrome
UN Sustainable Development Goals
  • Good health and well-being
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