article·Nature Genetics·Sep 1, 2022GREEN OA

Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data

MJMartin Jinye ZhangCorresponding authorKHKangcheng HouKKKushal K. DeySSSaori SakaueKAKarthik A. Jagadeesh

Broad Institute · Harvard University · +10 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

No abstract available for this paper.

Citation impact

265
total citations
FWCI
19.84
Percentile
100%
References
78
Citations per year

Authors

15
  • MJ
    Martin Jinye ZhangCorresponding

    Broad Institute, Harvard University

  • KH
    Kangcheng Hou

    University of California, Los Angeles

  • KK
    Kushal K. Dey

    Broad Institute, Harvard University

  • SS
    Saori Sakaue

    Broad Institute, Brigham and Women's Hospital, Harvard University

  • KA
    Karthik A. Jagadeesh

    Broad Institute, Harvard University

Topics & keywords

Topics
  • Primary topicSingle-cell and spatial transcriptomics100%
  • Extracellular vesicles in disease99%
  • Atherosclerosis and Cardiovascular Diseases96%
Keywords
  • Biology
  • RNA-Seq
  • Genetics
  • Disease
  • Computational biology
  • Cell
  • RNA
  • Transcriptome
No related works found for this paper.

Funding

  • NI
    National Institutes of Health
    Awards: R01MH123922, R01 HG006399, R01MH121521, R01 MH101244, UH2-AR067677, R01 MH115676, U01 HG009379, R01-AR063759, R37 MH107649, UC2-AR081023, U01 HG012009, P01-AI148102
  • MR
    Medical Research Council
    Award: MC_PC_17228
  • NH
    National Human Genome Research Institute
    Awards: K99HG012203, F32 HG011434-03