articleImmunityAug 1, 2016BRONZE OA

The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction

NENicole E. ScharpingAVAshley V. MenkRSRebecca S. MoreciRDRyan D. WhetstoneRDRebekah Dadey

University of Pittsburgh · UPMC Hillman Cancer Center

PubMed
Indexed incrossrefpubmed

Abstract

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780
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17.75
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100%
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44
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Authors

8

Topics & keywords

Topics
Keywords
  • Tumor microenvironment
  • Biology
  • Mitochondrial biogenesis
  • Cancer research
  • Tumor progression
  • Cell biology
  • Reprogramming
  • Cancer cell
UN Sustainable Development Goals
  • Zero hunger
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