Persistent Circulating Severe Acute Respiratory Syndrome Coronavirus 2 Spike Is Associated With Post-acute Coronavirus Disease 2019 Sequelae
Brigham and Women's Hospital · Harvard University · +2 more institutions
Abstract
The diagnosis of postacute sequelae of coronavirus disease 2019 (PASC) poses an ongoing medical challenge. To identify biomarkers associated with PASC we analyzed plasma samples collected from PASC and coronavirus disease 2019 patients to quantify viral antigens and inflammatory markers. We detect severe acute respiratory syndrome coronavirus 2 spike predominantly in PASC patients up to 12 months after diagnosis.
Citation impact
- FWCI
- 60.28
- Percentile
- 100%
- References
- 16
Authors
7- ZSZoe Swank
Brigham and Women's Hospital, Harvard University
- YSYasmeen Senussi
Brigham and Women's Hospital, Harvard University
- ZMZachary Manickas-Hill
Ragon Institute of MGH, MIT and Harvard
- XGXu G. Yu
Brigham and Women's Hospital, Harvard University, Ragon Institute of MGH, MIT and Harvard
- JZJonathan Z. Li
Brigham and Women's Hospital, Harvard University
Topics & keywords
- Medicine
- Coronavirus
- Coronavirus disease 2019 (COVID-19)
- Disease
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
- Coronaviridae
- Virology
- Respiratory disease
- Good health and well-being