reviewJournal of HepatologySep 5, 2022HYBRID OA

Alcohol consumption and metabolic syndrome: Clinical and epidemiological impact on liver disease

FÅFredrik ÅbergCDChristopher D. ByrneCJCarlos J. PirolaVMVille MännistöSSSilvia Sookoian

University of Helsinki · Helsinki University Hospital · +8 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

Alcohol use and metabolic syndrome are highly prevalent in the population and frequently co-exist. Both are implicated in a large range of health problems, including chronic liver disease, hepatocellular carcinoma, and liver-related outcomes (i.e. decompensation or liver transplantation). Studies have yielded mixed results regarding the effects of mild-moderate alcohol consumption on the risk of metabolic syndrome and fatty liver disease, possibly due to methodological differences. The few available prospective studies have indicated that mild-moderate alcohol use is associated with an increase in liver-related outcomes. This conclusion was substantiated by systems biology analyses suggesting that alcohol and…

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272
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38.40
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100%
References
167
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Authors

5

Topics & keywords

Topics
Keywords
  • Metabolic syndrome
  • Fatty liver
  • Liver disease
  • Medicine
  • Population
  • Chronic liver disease
  • Alcoholic liver disease
  • Physiology
UN Sustainable Development Goals
  • Good health and well-being
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