reviewMoleculesSep 5, 2022GOLD OA

Prostate Cancer Review: Genetics, Diagnosis, Treatment Options, and Alternative Approaches

University of the Free State · Central University of Technology · +1 more institution

PubMed
Indexed incrossrefdoajpubmed

Abstract

Prostate cancer is one of the malignancies that affects men and significantly contributes to increased mortality rates in men globally. Patients affected with prostate cancer present with either a localized or advanced disease. In this review, we aim to provide a holistic overview of prostate cancer, including the diagnosis of the disease, mutations leading to the onset and progression of the disease, and treatment options. Prostate cancer diagnoses include a digital rectal examination, prostate-specific antigen analysis, and prostate biopsies. Mutations in certain genes are linked to the onset, progression, and metastasis of the cancer. Treatment for localized prostate cancer encompasses active surveillance,…

Citation impact

834
total citations
FWCI
112.72
Percentile
100%
References
215
Citations per year

Authors

6

Topics & keywords

Keywords
  • Prostate cancer
  • Medicine
  • Prostatectomy
  • Oncology
  • Radiation therapy
  • Androgen deprivation therapy
  • Cancer
  • Disease
UN Sustainable Development Goals
  • Good health and well-being
No related works found for this paper.

Funding