reviewCell Communication and SignalingSep 19, 2022GOLD OA

A review on exosomes application in clinical trials: perspective, questions, and challenges

Urmia University · Urmia University of Medical Sciences · +2 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

Background

Exosomes are progressively known as significant mediators of cell-to-cell communication. They convey active biomolecules to target cells and have vital functions in several physiological and pathological processes, and show substantial promise as novel treatment strategies for diseases.

Methods

In this review study, we studied numerous articles over the past two decades published on application of exosomes in different diseases as well as on perspective and challenges in this field.

Citation impact

579
total citations
FWCI
44.44
Percentile
100%
References
85
Citations per year

Authors

3

Topics & keywords

Keywords
  • Microvesicles
  • Exosome
  • Clinical trial
  • Medicine
  • Biomarker
  • Mesenchymal stem cell
  • Drug delivery
  • Bioinformatics
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