Essential metals in health and disease
Constantine the Philosopher University in Nitra · Slovak University of Technology in Bratislava · +3 more institutions
Abstract
In total, twenty elements appear to be essential for the correct functioning of the human body, half of which are metals and half are non-metals. Among those metals that are currently considered to be essential for normal biological functioning are four main group elements, sodium (Na), potassium (K), magnesium (Mg), and calcium (Ca), and six d-block transition metal elements, manganese (Mn), iron (Fe), cobalt (Co), copper (Cu), zinc (Zn) and molybdenum (Mo). Cells have developed various metallo-regulatory mechanisms for maintaining a necessary homeostasis of metal-ions for diverse cellular processes, most importantly in the central nervous system. Since redox active transition metals (for example Fe and Cu)…
Citation impact
- FWCI
- 101.01
- Percentile
- 100%
- References
- 248
Authors
8Topics & keywords
- Chemistry
- Homeostasis
- Redox
- Manganese
- Transition metal
- Zinc
- Catalysis
- Radical