reviewFrontiers in MicrobiologySep 26, 2022GOLD OA

Human gut microbiota in health and disease: Unveiling the relationship

Government College University, Faisalabad · University of Agriculture Faisalabad · +3 more institutions

PubMed
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Abstract

The human gut possesses millions of microbes that define a complex microbial community. The gut microbiota has been characterized as a vital organ forming its multidirectional connecting axis with other organs. This gut microbiota axis is responsible for host-microbe interactions and works by communicating with the neural, endocrinal, humoral, immunological, and metabolic pathways. The human gut microorganisms (mostly non-pathogenic) have symbiotic host relationships and are usually associated with the host's immunity to defend against pathogenic invasion. The dysbiosis of the gut microbiota is therefore linked to various human diseases, such as anxiety, depression, hypertension, cardiovascular diseases,…

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