Advancing human gut microbiota research by considering gut transit time
University of Copenhagen · Vlaams Instituut voor Biotechnologie · +3 more institutions
Abstract
Accumulating evidence indicates that gut transit time is a key factor in shaping the gut microbiota composition and activity, which are linked to human health. Both population-wide and small-scale studies have identified transit time as a top covariate contributing to the large interindividual variation in the faecal microbiota composition. Despite this, transit time is still rarely being considered in the field of the human gut microbiome. Here, we review the latest research describing how and why whole gut and segmental transit times vary substantially between and within individuals, and how variations in gut transit time impact the gut microbiota composition, diversity and metabolism. Furthermore, we…
Citation impact
- FWCI
- 22.78
- Percentile
- 100%
- References
- 245
Authors
6Topics & keywords
- Gut flora
- Microbiome
- Biology
- Gut microbiome
- Transit time
- Population
- Immunology
- Bioinformatics