Update from the 2022 World Health Organization Classification of Thyroid Tumors: A Standardized Diagnostic Approach

The fifth edition of the World Health Organization (WHO) histologic classification of thyroid neoplasms released in 2022 includes newly recognized tumor types, subtypes, and a grading system. Follicular cell-derived neoplasms are categorized into three families (classes): benign tumors, low-risk neoplasms, and malignant neoplasms. The terms "follicular nodular disease" and "differentiated high-grade thyroid carcinoma" are introduced to account for multifocal hyperplastic/neoplastic lesions and differentiated thyroid carcinomas with high-grade features, respectively. The term "Hürthle cells" is replaced with "oncocytic cells." Invasive encapsulated follicular and cribriform morular variants of papillary thyroid…

• NR
  National Research Foundation
• MO
  Ministry of Health and Welfare

  Award: HI21C0940
• NR
  National Research Foundation of Korea

  Award: 2020R1F1A1070028
• MO
  Ministry of Science and ICT, South Korea