Zwitterionic Biomaterials

The term "zwitterionic polymers" refers to polymers that bear a pair of oppositely charged groups in their repeating units. When these oppositely charged groups are equally distributed at the molecular level, the molecules exhibit an overall neutral charge with a strong hydration effect via ionic solvation. The strong hydration effect constitutes the foundation of a series of exceptional properties of zwitterionic materials, including resistance to protein adsorption, lubrication at interfaces, promotion of protein stabilities, antifreezing in solutions, etc. As a result, zwitterionic materials have drawn great attention in biomedical and engineering applications in recent years. In this review, we give a…

• NS
  National Science Foundation

  Awards: 1806138, DMR 2002940, CBET 2103295, 2107619
• CU
  Cornell University
• NN
  National Natural Science Foundation of China

  Awards: 52103188, 22078238, 21621004, 21961132005, 22175152
• MO
  Ministry of Science and Technology of the People's Republic of China

  Awards: 2020YFE0204400, 2021YFC2100800
• CU
  Central University Basic Research Fund of China

  Award: 226-2022-00146
• AC
  American Chemical Society Petroleum Research Fund

  Award: 65277-ND7
• SK
  State Key Laboratory of Biochemical Engineering
• OO
  Office of Naval Research

  Award: N00014-20-1-2731
• NS
  Natural Science Foundation of Zhejiang Province

  Award: LHDMZ22H300011