articleOxygenOct 10, 2022DIAMOND OA

RONS and Oxidative Stress: An Overview of Basic Concepts

AKAna Karina Aranda‐RiveraACAlfredo Cruz‐GregorioYLYalith Lyzet Arancibia‐HernándezEYEstefani Yaquelin Hernández‐CruzJPJosé Pedraza‐Chaverrí

Universidad Nacional Autónoma de México

Indexed incrossrefdoaj

Abstract

Oxidative stress (OS) has greatly interested the research community in understanding damaging processes occurring in cells. OS is triggered by an imbalance between reactive oxygen species (ROS) production and their elimination by the antioxidant system; however, ROS function as second messengers under physiological conditions. ROS are produced from endogenous and exogenous sources. Endogenous sources involve mitochondria, nicotinamide adenine dinucleotide phosphate hydrogen (NADPH), oxidases (NOXs), endoplasmic reticulum (ER), xanthine oxidases (XO), endothelial nitric oxide synthase (eNOs), and others. In contrast, exogenous ROS might be generated through ultraviolet (UV) light, ionizing radiation (IR),…

Citation impact

346
total citations
FWCI
50.76
Percentile
100%
References
394
Citations per year

Authors

5

Topics & keywords

Topics
Keywords
  • Oxidative stress
  • Reactive oxygen species
  • Nicotinamide adenine dinucleotide phosphate
  • Antioxidant
  • Reactive nitrogen species
  • Chemistry
  • Biochemistry
  • Endogeny
No related works found for this paper.

Funding