In vivo fluorescence imaging: success in preclinical imaging paves the way for clinical applications
Baker Heart and Diabetes Institute · Swinburne University of Technology · +9 more institutions
Abstract
Advances in diagnostic imaging have provided unprecedented opportunities to detect diseases at early stages and with high reliability. Diagnostic imaging is also crucial to monitoring the progress or remission of disease and thus is often the central basis of therapeutic decision-making. Currently, several diagnostic imaging modalities (computed tomography, magnetic resonance imaging, and positron emission tomography, among others) are routinely used in clinics and present their own advantages and limitations. In vivo near-infrared (NIR) fluorescence imaging has recently emerged as an attractive imaging modality combining low cost, high sensitivity, and relative safety. As a preclinical tool, it can be used to…
Citation impact
- FWCI
- 17.24
- Percentile
- 100%
- References
- 163
Authors
8- ARAhmed RefaatCorresponding
Baker Heart and Diabetes Institute, Swinburne University of Technology, Alexandria University
- MLMay Lin Yap
Baker Heart and Diabetes Institute
- GAGeoffrey A. Pietersz
Baker Heart and Diabetes Institute, Burnet Institute, The University of Melbourne
- APAidan P. G. Walsh
Baker Heart and Diabetes Institute, Monash University
- JZJohannes Zeller
Baker Heart and Diabetes Institute, University of Freiburg, University Medical Center Freiburg
Topics & keywords
- Preclinical imaging
- Molecular imaging
- Positron emission tomography
- Magnetic resonance imaging
- Fluorescence-lifetime imaging microscopy
- Medical imaging
- Medicine
- Medical physics