Calcium Phosphate-Based Biomaterials for Bone Repair
Tongji University · Kunming Medical University · +2 more institutions
Abstract
Traumatic, tumoral, and infectious bone defects are common in clinics, and create a big burden on patient's families and society. Calcium phosphate (CaP)-based biomaterials have superior properties and have been widely used for bone defect repair, due to their similarities to the inorganic components of human bones. The biological performance of CaPs, as a determining factor for their applications, are dependent on their physicochemical properties. Hydroxyapatite (HAP) as the most thermally stable crystalline phase of CaP is mostly used in the form of ceramics or composites scaffolds with polymers. Nanostructured CaPs with large surface areas are suitable for drug/gene delivery systems. Additionally, CaP…
Citation impact
- FWCI
- 19.94
- Percentile
- 100%
- References
- 315
Authors
9- XHXiaodong Hou
Tongji University, Kunming Medical University, First Affiliated Hospital of Kunming Medical University, Shanghai Tenth People's Hospital
- LZLei Zhang
Tongji University, Shanghai Tenth People's Hospital
- ZZZifei ZhouCorresponding
Tongji University, Shanghai Tenth People's Hospital
- XLXiong Luo
Tongji University, Shanghai Tenth People's Hospital
- TWTianlong Wang
Tongji University, Shanghai Tenth People's Hospital
Topics & keywords
- Materials science
- Bone healing
- Nanotechnology
- Regeneration (biology)
- Drug delivery
- Polymer
- Biomedical engineering
- Composite material