Smartphone-Based Electrochemical Immunoassay for Point-of-Care Detection of SARS-CoV-2 Nucleocapsid Protein
Fuzhou University · Hubei University of Science and Technology · +3 more institutions
Abstract
Large-scale, rapid, and inexpensive serological diagnoses of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) are of great interest in reducing virus transmission at the population level; however, their development is greatly plagued by the lack of available point-of-care methods, leading to low detection efficiency. Herein, an ultrasensitive smartphone-based electrochemical immunoassay is reported for rapid (less than 5 min), low-cost, easy-to-implement detection of the SARS-CoV-2 nucleocapsid protein (SARS-CoV-2 N protein). Specifically, the electrochemical immunoassay was fabricated on a screen-printed carbon electrode coated with electrodeposited gold nanoparticles, followed by incubation of…
Citation impact
- FWCI
- 32.56
- Percentile
- 100%
- References
- 25
Authors
7Topics & keywords
- Chemistry
- Immunoassay
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
- Point-of-care testing
- Point of care
- Coronavirus disease 2019 (COVID-19)
- 2019-20 coronavirus outbreak
- Virology