ROS: Basic Concepts, Sources, Cellular Signaling, and its Implications in Aging Pathways

Reactive oxygen species (ROS) are bioproducts of cellular metabolism. There is a range of molecules with oxidizing properties known as ROS. Despite those molecules being implied negatively in aging and numerous diseases, their key role in cellular signaling is evident. ROS control several biological processes such as inflammation, proliferation, and cell death. The redox signaling underlying these cellular events is one characteristic of the new generation of scientists aimed at defining the role of ROS in the cellular environment. The control of redox potential, which includes the balance of the sources of ROS and the antioxidant system, implies an important target for understanding the cells' fate derived…

• CN
  Conselho Nacional de Desenvolvimento Científico e Tecnológico

  Awards: 04/2021-PQ, 47759.673.28850.11082021, 04/2021, PVG14861-2021, 311711/2018-9
• FD
  Fundação de Apoio à Pesquisa do Estado da Paraíba

  Awards: PVG14861-2021, 47759.673.28850.11082021, 311711/2018-9
• UF
  Universidade Federal da Paraíba

  Awards: PVG14861-2021, 311711/2018-9, 47759.673.28850.11082021
• PD
  Pró-Reitoria de Pesquisa, Universidade Federal do Rio Grande do Sul