Photothermal Hydrogel Encapsulating Intelligently Bacteria-Capturing Bio-MOF for Infectious Wound Healing
Wuhan University of Technology · Central South University · +3 more institutions
Abstract
Chronic wounds are characterized by long-term inflammation and persistent infection, which make them difficult to heal. Therefore, an urgent desire is to develop a multifunctional wound dressing that can prevent wound infection and promote wound healing by creating a favorable microenvironment. In this study, a curcumin-based metal–organic framework (QCSMOF-Van), loaded with vancomycin and coated with quaternary ammonium salt chitosan (QCS), was prepared. Multifunctional composite hydrogels were conveniently synthesized by combining methacrylic anhydride modified gelatin and methacrylic anhydride modified oxidized sodium alginate with QCSMOF-Van through radical polymerization and Schiff base reaction. It is…
Citation impact
- FWCI
- 27.52
- Percentile
- 100%
- References
- 67
Authors
9Topics & keywords
- Self-healing hydrogels
- Wound healing
- Regeneration (biology)
- Chitosan
- Materials science
- Chronic wound
- Bacteria
- Chemistry