Monkeypox: epidemiology, pathogenesis, treatment and prevention

Monkeypox is a zoonotic disease that was once endemic in west and central Africa caused by monkeypox virus. However, cases recently have been confirmed in many nonendemic countries outside of Africa. WHO declared the ongoing monkeypox outbreak to be a public health emergency of international concern on July 23, 2022, in the context of the COVID-19 pandemic. The rapidly increasing number of confirmed cases could pose a threat to the international community. Here, we review the epidemiology of monkeypox, monkeypox virus reservoirs, novel transmission patterns, mutations and mechanisms of viral infection, clinical characteristics, laboratory diagnosis and treatment measures. In addition, strategies for the…

• NN
  National Natural Science Foundation of China

  Awards: 81972878, 82172733
• NK
  National Key Research and Development Program of China

  Awards: 2016YFC1303403, 2020YFC0860200
• KR
  Key Research and Development Program of Sichuan Province

  Award: 2022ZDZX0024