Global SARS-CoV-2 seroprevalence from January 2020 to April 2022: A systematic review and meta-analysis of standardized population-based studies
World Health Organization · University of Calgary · +11 more institutions
Abstract
BACKGROUND: Our understanding of the global scale of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection remains incomplete: Routine surveillance data underestimate infection and cannot infer on population immunity; there is a predominance of asymptomatic infections, and uneven access to diagnostics. We meta-analyzed SARS-CoV-2 seroprevalence studies, standardized to those described in the World Health Organization's Unity protocol (WHO Unity) for general population seroepidemiological studies, to estimate the extent of population infection and seropositivity to the virus 2 years into the pandemic. METHODS AND FINDINGS: We conducted a systematic review and meta-analysis, searching MEDLINE,…
Citation impact
- FWCI
- 29.03
- Percentile
- 100%
- References
- 49
Authors
30Topics & keywords
- Seroprevalence
- Medicine
- Population
- Meta-analysis
- Pandemic
- Checklist
- Cohort study
- Demography
Funding
- PHPublic Health Agency of CanadaAward: 2021-HQ-000056
- KIKoch Institute for Integrative Cancer Research, Massachusetts Institute of Technology
- ECEuropean Centre for Disease Prevention and Control
- PHPublic Health Agency
- BFBundesministerium für Gesundheit
- CMCanadian Medical Association
- RKRobert Koch Institut
- CFCenters for Disease Control and Prevention