Toxicity of metal-based nanoparticles: Challenges in the nano era

With the rapid progress of nanotechnology, various nanoparticles (NPs) have been applicated in our daily life. In the field of nanotechnology, metal-based NPs are an important component of engineered NPs, including metal and metal oxide NPs, with a variety of biomedical applications. However, the unique physicochemical properties of metal-based NPs confer not only promising biological effects but also pose unexpected toxic threats to human body at the same time. For safer application of metal-based NPs in humans, we should have a comprehensive understanding of NP toxicity. In this review, we summarize our current knowledge about metal-based NPs, including the physicochemical properties affecting their…

• NN
  National Natural Science Foundation of China

  Awards: 81670433, 81970398
• NS
  Natural Science Foundation of Zhejiang Province

  Awards: LQ20H020008, LR22H020002, Q20H020059
• SF
  Science Fund for Distinguished Young Scholars of Zhejiang Province

  Award: LR22H020002