CAMPR4: a database of natural and synthetic antimicrobial peptides

There has been an exponential increase in the design of synthetic antimicrobial peptides (AMPs) for its use as novel antibiotics. Synthetic AMPs are substantially enriched in residues with physicochemical properties known to be critical for antimicrobial activity; such as positive charge, hydrophobicity, and higher alpha helical propensity. The current prediction algorithms for AMPs have been developed using AMP sequences from natural sources and hence do not perform well for synthetic peptides. In this version of CAMP database, along with updating sequence information of AMPs, we have created separate prediction algorithms for natural and synthetic AMPs. CAMPR4 holds 24243 AMP sequences, 933 structures, 2143…

• UO
  University of Oxford
• DO
  Department of Biotechnology, Ministry of Science and Technology, India

  Award: BT/PR40165/BTIS/137/12/2021
• IC
  Indian Council of Medical Research

  Award: BT/PR40165/BTIS/137/12/2021
• DO
  Department of Biotechnology, Government of West Bengal

  Award: RA/1121/09-2021