articleNature CommunicationsNov 16, 2022GOLD OA

Global disparities in SARS-CoV-2 genomic surveillance

AFAnderson F. BritoESElizaveta SemenovaGDGytis DudasGWGabriel W. HasslerCCChaney C. Kalinich

Yale University · Instituto de Saúde · +54 more institutions

PubMed
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Abstract

Genomic sequencing is essential to track the evolution and spread of SARS-CoV-2, optimize molecular tests, treatments, vaccines, and guide public health responses. To investigate the global SARS-CoV-2 genomic surveillance, we used sequences shared via GISAID to estimate the impact of sequencing intensity and turnaround times on variant detection in 189 countries. In the first two years of the pandemic, 78% of high-income countries sequenced >0.5% of their COVID-19 cases, while 42% of low- and middle-income countries reached that mark. Around 25% of the genomes from high income countries were submitted within 21 days, a pattern observed in 5% of the genomes from low- and middle-income countries. We found that…

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Topics & keywords

Topics
Keywords
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
  • Sars virus
  • Coronavirus disease 2019 (COVID-19)
  • 2019-20 coronavirus outbreak
  • Virology
  • Pandemic
  • Betacoronavirus
  • Computational biology
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