GENCODE: reference annotation for the human and mouse genomes in 2023

Abstract GENCODE produces high quality gene and transcript annotation for the human and mouse genomes. All GENCODE annotation is supported by experimental data and serves as a reference for genome biology and clinical genomics. The GENCODE consortium generates targeted experimental data, develops bioinformatic tools and carries out analyses that, along with externally produced data and methods, support the identification and annotation of transcript structures and the determination of their function. Here, we present an update on the annotation of human and mouse genes, including developments in the tools, data, analyses and major collaborations which underpin this progress. For example, we report the creation…

• WT
  Wellcome Trust

  Award: WT222155/Z/20/Z
• EM
  European Molecular Biology Laboratory
• NI
  National Institutes of Health

  Awards: U41HG007234, R01HG004037
• BA
  Biotechnology and Biological Sciences Research Council

  Award: BB/T01461X/1